三级aa视频在线观看-三级国产-三级国产精品一区二区-三级国产三级在线-三级国产在线

Global EditionASIA 中文雙語Fran?ais
China
Home / China / Health

Chinese scientists reveal discovery of osteoarthritis pathogenesis mechanism

Xinhua | Updated: 2025-04-11 08:51
Share
Share - WeChat
[Photo/cas.cn]

BEIJING -- A Chinese research team has uncovered a previously unknown "gut-joint axis" mechanism that drives osteoarthritis, revolutionizing the understanding of this degenerative joint disease, according to the Chinese Academy of Sciences.

The current understanding of osteoarthritis pathogenesis remains incomplete, and no safe, effective disease-modifying drugs are available at present. Identifying disease mechanisms and therapeutic targets, and developing treatments are active research priorities.

While osteoarthritis manifests as localized joint degeneration, previous focus on localized factors as core etiology has meant that systemic contributors are poorly understood.

By analyzing two independent Chinese cohorts, researchers from the CAS' Shanghai Institute of Materia Medica and Xiangya Hospital of Central South University found that osteoarthritis patients had significantly lower blood levels of bile acid GUDCA, which correlated with disease severity.

Animal experiments demonstrated that GUDCA alleviates osteoarthritis by inhibiting the intestinal FXR receptor and increasing glucagon-like peptide-1 (GLP-1) production.

Published in Science with an accompanying commentary, the results of the research provide clinical evidence that can be used to target the gut-joint axis in osteoarthritis treatment and break the established theory that osteoarthritis is caused by local factors.

Top
BACK TO THE TOP
English
Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
主站蜘蛛池模板: 又大又紧又硬又湿a视频 | 日韩高清在线免费观看 | 免费人成综合在线视频 | 欧美v亚洲 | 日韩欧美一区二区三区免费观看 | 亚洲欧美在线免费观看 | 国产成人综合在线观看网站 | 欧美男女激情 | 8090碰成年女人免费碰碰尤物 | 亚洲综合套图 | 久久99国产精品久久99无号码 | 国产成人久久精品 | jizz国产精品免费麻豆 | 国产福利足控交在线观看 | 国产男人午夜视频在线观看 | 国产一区二区免费福利片 | 色屁屁www欧美激情在线观看 | 午夜视频网址 | 性生活大片免费看 | 精品国内一区二区三区免费视频 | 亚洲国产精品一区二区三区在线观看 | 国产大片中文字幕在线观看 | 中国一级做a爰片久久毛片 中国一级做a爱片免费 | 国产精品尤物在线 | 拍拍视频免费观看网站在线观看 | 成人黄色在线视频 | 国产精品青草久久久久婷婷 | 欧美色碰碰碰免费观看长视频 | 国产成人禁片免费观看视频 | 国产乱熟肥女视频网站 | 国产在线观看网址你懂得 | 特级毛片a级毛免费播放 | 亚洲国产精品一区二区第一页 | 毛片免费观看久久欧美 | 午夜国产精品免费观看 | 亚洲精品区在线播放一区二区 | 亚洲一级毛片在线观 | 欧美特黄一区二区三区 | 亚洲经典一区 | 亚洲精品视频在线观看视频 | 国内真实下药迷j在线观看 国内主播大秀福利视频在线看 |